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Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

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Date

2014

Authors

Chatzigeorgiou, Antonios
Seijkens, Tom
Zarzycka, Barbara
Engel, David
Poggi, Marjorie
van den Berg, Susan
van den Berg, Sjoerd
Soehnlein, Oliver
Winkels, Holger
Beckers, Linda

Journal Title

Journal ISSN

Volume Title

Publisher

National Academy of Sciences (USA)

Abstract

The immune system plays an instrumental role in obesity and insulin resistance. Here, we unravel the role of the costimulatory molecule CD40 and its signaling intermediates, TNF receptor-associated factors (TRAFs), in diet-induced obesity (DIO). Although

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Keywords

Citation

URI

http://hdl.handle.net/1885/35783

Collections

ANU Research Publications

Source

PNAS - Proceedings of the National Academy of Sciences of the United States of America

Type

Journal article

Book Title

Entity type

Access Statement

Open Access

License Rights

DOI

10.1073/pnas.1400419111/-/DCSupplemental

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01_Chatzigeorgiou_Blocking_CD40-TRAF6_signaling_2014.pdf (1.82 MB)

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