Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory

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Authors

Martin, Stephen
Goodnow, Christopher

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Nature Publishing Group

Abstract

The basis of immune memory leading to heightened secondary antibody responses is a longstanding unanswered issue. Here we show that a single irreversible molecular change in the B cell antigen receptor, which is brought about by immunoglobulin M (IgM) to

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Nature Immunology

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Restricted until

2037-12-31