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It takes two transposons to tango: transposable-element-mediated chromosomal rearrangements.

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dc.contributor.authorGray, Y H M
dc.date.accessioned2015-12-13T23:15:41Z
dc.date.issued2000
dc.date.updated2015-12-12T08:44:35Z
dc.description.abstractTransposable elements (TEs) promote various chromosomal rearrangements more efficiently, and often more specifically, than other cellular processes1-3. One explanation of such events is homologous recombination between multiple copies of a TE present in a genome. Although this does occur, strong evidence from a number of TE systems in bacteria, plants and animals suggests that another mechanism - alternative transposition - induces a large proportion of TE-associated chromosomal rearrangements. This paper reviews evidence for alternative transposition from a number of unrelated but structurally similar TEs. The similarities between alternative transposition and V(D)J recombination are also discussed, as is the use of alternative transposition as a genetic tool.
dc.identifier.issn0168-9525
dc.identifier.urihttp://hdl.handle.net/1885/89003
dc.publisherElsevier
dc.sourceTrends in Genetics
dc.subjectKeywords: animal; bacterium; chromosome rearrangement; chromosome replication; genetic recombination; genome; nonhuman; plant; priority journal; review; technique; transposon; Animal; Chromosomes; Comparative Study; DNA Nucleotidyltransferases; DNA Transposable Ele
dc.titleIt takes two transposons to tango: transposable-element-mediated chromosomal rearrangements.
dc.typeJournal article
local.bibliographicCitation.lastpage468
local.bibliographicCitation.startpage461
local.contributor.affiliationGray, Y H M, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidGray, Y H M, u9800691
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor100103 - Agricultural Molecular Engineering of Nucleic Acids and Proteins
local.identifier.ariespublicationMigratedxPub18891
local.identifier.citationvolume16
local.identifier.doi10.1016/S0168-9525(00)02104-1
local.identifier.scopusID2-s2.0-0034307716
local.type.statusPublished Version

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