A composite polynomial approach for analyzing the indefinite self-association of macromolecules studied by sedimentation equilibrium

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dc.contributor.authorHall, Damien
dc.date.accessioned2020-09-21T00:31:14Z
dc.date.issued2017
dc.date.updated2020-06-23T00:56:10Z
dc.description.abstractA different approach is described for analyzing sedimentation equilibrium experiments of indefinitely self-associating systems. The procedure involves application of conservation of mass criteria, along with local evaluation of the weight average molar mass, to generate a polynomial based on a composite pseudo-independent variable. The outlined method does not depend upon non-linear regression to generate a solution, but instead requires evaluation of the roots of a high-order polynomial.en_AU
dc.description.sponsorshipThis work was jointly funded by an Australian National University Senior Research Fellowship and an Osaka University Cross-Appointment as an Associate Professor. Further grant assistance was provided by the Osaka University Multiscale Structural Biology Program awarded to Prof. Junichi Takagi and Damien Hall.en_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn0301-4622en_AU
dc.identifier.urihttp://hdl.handle.net/1885/210662
dc.language.isoen_AUen_AU
dc.publisherElsevieren_AU
dc.rightsCrown Copyright © 2017 Published by Elsevier B.V.en_AU
dc.sourceBiophysical Chemistryen_AU
dc.titleA composite polynomial approach for analyzing the indefinite self-association of macromolecules studied by sedimentation equilibriumen_AU
dc.typeJournal articleen_AU
local.bibliographicCitation.lastpage16en_AU
local.bibliographicCitation.startpage10en_AU
local.contributor.affiliationHall, Damien, College of Science, ANUen_AU
local.contributor.authoruidHall, Damien, u5468311en_AU
local.description.embargo2037-12-31
local.description.notesImported from ARIESen_AU
local.identifier.absfor030699 - Physical Chemistry not elsewhere classifieden_AU
local.identifier.absseo970103 - Expanding Knowledge in the Chemical Sciencesen_AU
local.identifier.ariespublicationu4485658xPUB651en_AU
local.identifier.citationvolume228en_AU
local.identifier.doi10.1016/j.bpc.2017.06.002en_AU
local.identifier.thomsonID000407980700002
local.publisher.urlhttps://www.elsevier.com/en-auen_AU
local.type.statusPublished Versionen_AU

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