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Islet Heparan Sulfate but Not Heparan Sulfate Proteoglycan Core Protein Is Lost During Islet Isolation and Undergoes Recovery Post-Islet Transplantation

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Authors

Choong, Fui Jiun
Freeman, Craig
Simeonovic, Charmaine
Parish, Christopher

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Publisher

Wiley-Blackwell

Abstract

Islet beta cells in situ express intracellular heparan sulfate (HS), a property previously shown in vitro to be important for their survival. We report that HS levels inside islet beta cells correlate with the novel intracellular localization of the HSPG

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Source

American Journal of Transplantation

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Restricted until

2037-12-31