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Engineering the male-specificity of Fab against SDM antigen by chain shuffling

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Date

2013

Authors

Wang, Naidong
Yuan, Anwen
Deng, Zhibang
Yang, Qing
Ma, Jun
Tan, Qinghui
Zhang, Sizhe
Xue, Liqun
Cui, Shuliang

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier BV

Abstract

High-titer serologically detected male (SDM) antibody fragments are essential for specific binding to the SDM antigen and promoting its application. The A8 clone previously obtained from an original phage antibody library was further affinity-matured by l

Description

Keywords

Keywords: Antibody repertoire; Chain shuffling; Phage display library; Recombinant antibody; SDM antigen

Citation

URI

http://hdl.handle.net/1885/63813

Collections

ANU Research Publications

Source

Theriogenology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.theriogenology.2013.02.012

Restricted until

2037-12-31

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