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Growth factor TGF- β induces intestinal epithelial cell (IEC-6) differentiation: MiR-146b as a regulatory component in the negative feedback loop

Date

Authors

Liao, Yalin

Zhang, Man

Lonnerdal, Bo

Publisher

Springer

Abstract

TGF-β is a potent pleiotropic factor that promotes small intestinal cell differentiation. The role of microRNAs in the TGF-β induction of intestinal epithelial phenotype is largely unknown. We hypothesized that microRNAs are functionally involved in TGF

Keywords

Keywords: alkaline phosphatase; microRNA; microRNA 146b; microsomal aminopeptidase; mitogen activated protein kinase 1; mitogen activated protein kinase 3; protein SIAH2; Smad7 protein; transforming growth factor beta; ubiquitin protein ligase E3; unclassified drug Differentiation; IEC-6 cell; microRNA array; miR-146b; SIAH2; TGF-ß

URI

http://hdl.handle.net/1885/74245

Collections

ANU Research Publications

Source

Genes & Nutrition

Type

Journal article

DOI

10.1007/s12263-012-0297-3

Restricted until

2037-12-31

Downloads

File

Description

01_Liao_Growth_factor_TGF-_β_induces_2013.pdf (611.06 KB)