HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products
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Authors
Pasquetto, Valerie
Bui, Huynh-Hoa
Giannino, Rielle
Peters, Bjoern
Mirza, Fareed
Sidney, John
Oseroff, Carla
Tscharke, David
Irvine, Kari R
Bennink, Jack R
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American Association of Immunologists
Abstract
In virus models explored in detail in mice, CTL typically focus on a few immunodominant determinants. In this study we use a multipronged approach to understand the diversity of CTL responses to vaccinia virus, a prototypic poxvirus with a genome ∼20-fo
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Journal of Immunology
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2037-12-31