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Homocysteine and the Brain in Midadult Life : Evidence for an increase risk of leukoaraiosis in men

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Date

2004

Authors

Sachdev, Perminder Singh
Parslow, Ruth
Salonikas, Chris
Lux, Ora
Wen, Wei
Kumar, Rajeev
Naidoo, Daya
Christensen, Helen
Jorm, Anthony F

Journal Title

Journal ISSN

Volume Title

Publisher

American Medical Association

Abstract

Background: High serum homocysteine (HCY) levels have been associated with thromboembolic cerebrovascular disease, but their relationship to microvascular disease is uncertain. Homocysteine also has a direct neurotoxic effect and has been linked to brain

Description

Keywords

Keywords: creatinine; cyanocobalamin; folic acid; homocysteine; thyrotropin; adult; Alzheimer disease; article; Australia; brain; brain atrophy; brain atrophy index; cerebrovascular disease; cognition; cognitive defect; controlled study; deep white matter hyperinte

Citation

URI

http://hdl.handle.net/1885/77435

Collections

ANU Research Publications

Source

Archives of Neurology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1001/archneur.61.9.1369

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