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A PCR birth process subject to an enzyme death process

Date

Authors

Gani, Joseph

Swift, R.J.

Publisher

Grace Scientific Publishing

Abstract

The PCR process is modelled as a birth process for DNA strands, subject to a death process for enzymes. The case of 1 DNA strand and 1 enzyme is considered first, and generalized to the n strand and b enzyme case. Finally an approximate process is considered which gives a good approximation for the expected number of DNA strands.

Keywords

Keywords: Birth process; Death process; DNA polymerase; Gompertz growth law; Polymerisation chain reaction (PCR)

URI

http://hdl.handle.net/1885/60533

Collections

ANU Research Publications

Source

Journal of Statistical Theory and Practice

Type

Journal article

DOI

10.1080/15598608.2011.10412036

Restricted until

2037-12-31

Downloads

File

Description

01_Gani_A_PCR_birth_process_subject_to_2011.pdf (158.07 KB)

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