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The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na + channel α,β,γ -ENaC

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Date

2003

Authors

Friedrich, Bjorn
Feng, Yan
Cohen, P
Risler, T
Vandewalle, A
Broer, Stefan
Wang, J
Pearce, D
Lang, Florian

Journal Title

Journal ISSN

Volume Title

Publisher

Springer

Abstract

The serum- and glucocorticoid-inducible kinase 1 (SGK1) has been identified as a signalling molecule up-regulated by aldosterone, which stimulates the renal epithelial Na+ channel ENaC. It is therefore thought to participate in the antinatriuretic action

Description

Keywords

Keywords: aldosterone; amiloride; glucocorticoid inducible kinase 2; glucocorticoid inducible kinase 3; isoenzyme; protein serine threonine kinase; protein subunit; serum and glucocorticoid regulated kinase 1; sodium channel; unclassified drug; animal cell; article ENaC; Kidney; Protein kinases; Sodium channel; Sodium reabsorption

Citation

URI

http://hdl.handle.net/1885/86568

Collections

ANU Research Publications

Source

Pflugers Archives European Journal of Physiology

Type

Journal article

Book Title

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