Positron emission tomography (PET) imaging of neuroblastoma and melanoma with  64 Cu-SarAr immunoconjugates

Voss, Stephan D; Smith, Suzanne; DiBartolo, Nadine; McIntosh, Lacey J; Cyr, Erika M; Bonab, Ali A; Dearling, Jason L J; Carter, Edward A; Fischman, Alan J; Treves, S Ted; Gillies, Stephen D; Sargeson, Alan; Huston, James S; Packard, Alan B

Positron emission tomography (PET) imaging of neuroblastoma and melanoma with 64 Cu-SarAr immunoconjugates

Date

2007

Authors

Voss, Stephan D

Smith, Suzanne

DiBartolo, Nadine

McIntosh, Lacey J

Cyr, Erika M

Bonab, Ali A

Dearling, Jason L J

Carter, Edward A

Fischman, Alan J

Treves, S Ted

Publisher

National Academy of Sciences (USA)

Abstract

The advancement of positron emission tomography (PET) depends on the development of new radiotracers that will complement 18F-FDG. Copper-64 (64Cu) is a promising PET radionuclide, particularly for antibody-targeted imaging, but the high in vivo lability