Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Protective CD8+ T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response

Date

Authors

Overstreet, Michael G

Cockburn, Ian

Zavala, Fidel

Publisher

Munksgaard International Publishers

Abstract

Immunization with high doses of irradiated sporozoites delivered by the bites of infected mosquitoes has been shown to induce protective responses against malaria, mediated in part by CD8+ T cells. In contrast, natural transmission involving low exposure

Keywords

Keywords: CD4 antigen; circumsporozoite protein; CD8+ T lymphocyte; cell protection; host parasite interaction; immune response; immunization; immunobiology; liver; liver cell; malaria; memory T lymphocyte; nonhuman; Plasmodium; priority journal; review; sporozoite CD8+ T cells; Liver; Lymph node; Malaria; Memory; Sporozoite

URI

http://hdl.handle.net/1885/33681

Collections

ANU Research Publications

Source

Immunological Reviews

Type

Journal article

DOI

10.1111/j.1600-065X.2008.00671.x.Review

Restricted until

2037-12-31

Downloads

File

Description

01_Overstreet_Protective_CD8+_T_cells_2008.pdf (331.08 KB)