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Conformation of Prion Protein Repeat Peptides Probed by FRET Measurements and Molecular Dynamics Simulations

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Gustiananda, Marsia
Liggins, John
Cummins, Peter
Gready, Jill

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Biophysical Society

Abstract

We report the combined use of steady-state fluorescence resonance energy transfer (FRET) experiments and molecular dynamics (MD) simulations to investigate conformational distributions of the prion protein (PrP) repeat system. FRET was used for the first

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Biophysical Journal

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2037-12-31