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The Synthesis and Biological Evaluation of Two Analogues of the C -Riboside Showdomycin

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Date

2005

Authors

Renner, Jens
Kruszelnicki, Irma
Adamiak, Beata
Willis, Anthony
Hammond, Edward
Su, Stephen
Burns, Christopher
Trybala, Edward
Ferro, Vito
Banwell, Martin

Journal Title

Journal ISSN

Volume Title

Publisher

CSIRO Publishing

Abstract

Two novel analogues, 2 and 3, of the C-riboside showdomycin (1) have been prepared by exploiting the N-TIPS-substituted pyrrole 7 as a synthetic equivalent for the maleimide C3 anion. The tetraacetate precursor, 12, of target 2 as well as target 3 itself

Description

Keywords

Keywords: Assays; Cells; Crystallography; Diffractometers; Diffusion; Dyes; Monolayers; Nitrogen compounds; Proteins; Solvents; Substitution reactions; Synthesis (chemical); X ray analysis; Anti-viral effects; C-nucleosides; C-riboside showdomycin; Flash chromatogr

Citation

URI

http://hdl.handle.net/1885/88750

Collections

ANU Research Publications

Source

Australian Journal of Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1071/CH04273

Restricted until

2037-12-31

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01_Renner_The_Synthesis_and_Biological_2005.pdf (300.45 KB)

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