Homocysteine and cognitive performance: Modification by the ApoE genotype

Elias, Merrill F; Robbins, Michael A; Budge, Marc; Elias, Penelope K; Dore, Gregory A; Brennan, Suzanne L; Johnston, Carole; Nagy, Zsuzsanna

Homocysteine and cognitive performance: Modification by the ApoE genotype

Date

2007

Authors

Elias, Merrill F

Robbins, Michael A

Budge, Marc

Elias, Penelope K

Dore, Gregory A

Brennan, Suzanne L

Johnston, Carole

Nagy, Zsuzsanna

Publisher

Elsevier

Abstract

We hypothesized that the magnitude of the association between plasma homocysteine concentration and cognitive performance is larger for ApoE-ε4 carriers than for non-carriers. Nine hundred eleven dementia-free and stroke-free subjects (59% women) from th