Assembly of polyamines via amino acids from three components using cobalt(III) template methodology.

Date

2002

Authors

Laval, Gilles
Clegg, William
Crane, Christopher
Hammershoi, Anders
Sargeson, Alan
Golding, Bernard

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

A versatile and efficient template synthesis has been developed to synthesise novel polyamines [e.g. rac-N3-(3-aminopropyl)butane-1,3-diamine, isospermidine 1] via amino acids [e.g. (2R,4S/2S,4R)-N4-(3-aminopropyl)-2,4-di-aminopentanoic acid] using cobalt(III) to assemble the three precursor components in a biomimetic manner.

Description

Keywords

Keywords: cobalt; n 3 (aminopropyl)butane 1,3 diamine; n 4 (3 aminopropyl) 2,4 diaminopentanoic acid; polyamine derivative; spermidine derivative; unclassified drug; valeric acid derivative; article; biomimetics; drug structure; drug synthesis; methodology; precurs

Citation

Source

Chemical Communications

Type

Journal article

Book Title

Entity type

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