Assembly of polyamines via amino acids from three components using cobalt(III) template methodology.
Date
2002
Authors
Laval, Gilles
Clegg, William
Crane, Christopher
Hammershoi, Anders
Sargeson, Alan
Golding, Bernard
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
A versatile and efficient template synthesis has been developed to synthesise novel polyamines [e.g. rac-N3-(3-aminopropyl)butane-1,3-diamine, isospermidine 1] via amino acids [e.g. (2R,4S/2S,4R)-N4-(3-aminopropyl)-2,4-di-aminopentanoic acid] using cobalt(III) to assemble the three precursor components in a biomimetic manner.
Description
Keywords
Keywords: cobalt; n 3 (aminopropyl)butane 1,3 diamine; n 4 (3 aminopropyl) 2,4 diaminopentanoic acid; polyamine derivative; spermidine derivative; unclassified drug; valeric acid derivative; article; biomimetics; drug structure; drug synthesis; methodology; precurs
Citation
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Source
Chemical Communications
Type
Journal article