NMR Structure of Citrobacter freundii AmpD, Comparison with Bacteriophage T7 Lysozyme and Homology with PGRP Domains
Date
2003
Authors
Liepinsh, Edvards
Gastaud, J.
Dehareng, Dominique
Joris, Bernard
Otting, Gottfried
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
AmpD is a bacterial amidase involved in the recycling of cell-wall fragments in Gram-negative bacteria. Inactivation of AmpD leads to derepression of β-lactamase expression, presenting a major pathway for the acquisition of constitutive antibiotic resist
Description
Keywords
Keywords: adenosine monophosphate deaminase; amidase; lysozyme; peptidoglycan recognition protein; protein; unclassified drug; zinc; article; bacteriophage T7; Citrobacter freundii; comparative study; enzyme activity; nuclear magnetic resonance; priority journal; p ß-lactamase induction; AmpD; NMR structure; Peptidoglycan recognition protein domain; Zinc amidase
Citation
Collections
Source
Journal of Molecular Biology
Type
Journal article