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Interferon-alpha (Intron A) upregulates urokinase-type plasminogen activator receptor gene expression

Date

Authors

Wu, Shanshan

Murrell, George

Wang, Yang

Publisher

Springer

Abstract

The regulation of urokinase plasminogen activator receptor (uPAR) gene expression by interferon-alpha (IFN-α, or Intron A) and interferon-gamma (IFN-γ) was studied in a HCT116 colon cancer cell line. uPAR mRNA levels were increased in a dose- and time-d

Keywords

Keywords: alpha interferon; amiloride; butyric acid; cycloheximide; gamma interferon; messenger RNA; recombinant alpha2b interferon; urokinase receptor; article; cancer cell; cell stimulation; colon cancer; controlled study; dose time effect relation; drug effect; Colon cancer cell; Gene expression; Interferon (IFN); Urokinase-type plasminogen activator receptor (uPAR)

URI

http://hdl.handle.net/1885/94260

Collections

ANU Research Publications

Source

Cancer Immunology, Immunotherapy: other biological response modifications

Type

Journal article

DOI

10.1007/s00262-002-0275-5

Restricted until

2037-12-31

Downloads

File

Description

01_Wu_Interferon-alpha_(Intron_A)_2002.pdf (173.62 KB)

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