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A Triple-challenge Mouse Model of Allergic Airway Disease, Primary Influenza Infection, and Secondary Bacterial Infection

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dc.contributor.authorRoberts, Sean
dc.contributor.authorWilliams, Clare
dc.contributor.authorRoy, Sreeja
dc.contributor.authorFuruya, Yoichi
dc.date.accessioned2023-09-05T04:17:51Z
dc.date.available2023-09-05T04:17:51Z
dc.date.issued2020
dc.date.updated2022-07-24T08:22:16Z
dc.description.abstractAsthma is a global problem that affects millions of individuals. An increased risk of respiratory viral and bacterial infections is one of the complications of asthma. We recently reported that mice with ovalbumin-induced allergic airway disease (AAD) are protected against influenza-Streptococcus pneumoniae co-infection. Here, we describe in detail a protocol on how to induce AAD and influenza-S. pneumoniae co-infection in mice and to evaluate the specific roles of asthma on immunity to viral and bacterial pathogens in the hope of translating findings to benefit asthmatic individuals.en_AU
dc.description.sponsorshipAn abbreviated protocol was previously published in Roberts et al. (2019). Y. F. was supported by the American Lung Association Biomedical Research Grant (RG341974) and is supported by American Heart Association Scientist Development Grant (17SDG33630188) and NIH (1R56AI146434-01).en_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn2331-8325en_AU
dc.identifier.urihttp://hdl.handle.net/1885/298232
dc.language.isoen_AUen_AU
dc.provenancehttps://v2.sherpa.ac.uk/id/publication/33293/..."published version can be archived in institutional repository" from SHERPA/RoMEO site as at 05/09/2023en_AU
dc.publisherBio-Protocolen_AU
dc.rights© 2020 The authorsen_AU
dc.sourceBio-Protocolen_AU
dc.subjectAsthmaen_AU
dc.subjectAllergic airway diseaseen_AU
dc.subjectInfluenzaen_AU
dc.subjectStreptococcus pneumoniaeen_AU
dc.subjectCo-infectionen_AU
dc.titleA Triple-challenge Mouse Model of Allergic Airway Disease, Primary Influenza Infection, and Secondary Bacterial Infectionen_AU
dc.typeJournal articleen_AU
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.issue8en_AU
local.bibliographicCitation.lastpage8en_AU
local.bibliographicCitation.startpage1en_AU
local.contributor.affiliationRoberts, Sean, Albany Medical Collegeen_AU
local.contributor.affiliationWilliams, Clare, Albany Medical Collegeen_AU
local.contributor.affiliationRoy, Sreeja, College of Health and Medicine, ANUen_AU
local.contributor.affiliationFuruya, Yoichi, Albany Medical Collegeen_AU
local.contributor.authoruidRoy, Sreeja, u4383446en_AU
local.description.notesImported from ARIESen_AU
local.identifier.absfor320401 - Allergyen_AU
local.identifier.absfor320701 - Medical bacteriologyen_AU
local.identifier.absfor320705 - Medical virologyen_AU
local.identifier.ariespublicationu9803255xPUB2848en_AU
local.identifier.citationvolume10en_AU
local.identifier.doi10.21769/BioProtoc.3583en_AU
local.identifier.thomsonIDWOS:000583098900001
local.publisher.urlhttps://en.bio-protocol.org/en_AU
local.type.statusPublished Versionen_AU

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