T Cell-Independent and Toll-like Receptor-Dependent Antigen-Driven Activation of Autoreactive B Cells
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Herlands, Robin A.
Christensen, Sean R.
Sweet, Rebecca
Hershberg, Uri
Shlomchik, M J
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Cell Press
Abstract
On the lupus-prone MRL-lpr/lpr (MRL-lpr) background, AM14 rheumatoid factor (RF) B cells are activated, differentiate into plasmablasts, and undergo somatic hypermutation outside of follicles. Using multiple strategies to impair T cells, we found that su
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Immunity
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2037-12-31
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