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Total and Regional Gray Matter Volume Is Not Related to APOE*E4 Status in a Community Sample of Middle-Aged Individuals

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Date

2008

Authors

Cherbuin, Nicolas
Sachdev, Perminder Singh
Maller, Jerome
Meslin, Chantal
Mack, Holly
Wen, Wei
Easteal, Simon
Anstey, Kaarin

Journal Title

Journal ISSN

Volume Title

Publisher

Oxford University Press

Abstract

Background. The APOE*E4 allele has been associated with greater gray matter atrophy and with Alzheimer's disease. The aim of this study was to investigate whether the relationship between cerebral gray matter atrophy and APOE*E4 genotype was also present

Description

Keywords

Keywords: apolipoprotein E4; adult; allele; amygdaloid nucleus; article; brain atrophy; brain region; brain size; community sample; controlled study; female; gene frequency; genotype; gray matter; heterozygote; hippocampus; human; male; morphometrics; nuclear magne Amygdala; APOE; Cerebral atrophy; Hippocampus; MRI; Voxel-based morphometry

Citation

URI

http://hdl.handle.net/1885/34606

Collections

ANU Research Publications

Source

Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Type

Journal article

Book Title

Entity type

Access Statement

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DOI

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