The Au(I)-Catalyzed Intramolecular Hydroarylation of Terminal Alkynes Under Mild Conditions: Application to the Synthesis of 2 H -Chromenes, Coumarins, Benzofurans, and Dihydroquinolines
Date
2009
Authors
Menon, Rajeev
Findlay, Alison
Bissember, Alexander
Banwell, Martin
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American Chemical Society
Abstract
(Chemical Equation Presented) Operationally simple Au(I)-catalyzed intramolecular hydroarylation (IMHA) reactions of terminal alkynes that proceed in high yield and under very mild conditions are described. These processes involve low catalyst loadings, mild reaction temperatures, and short reaction times, require no cocatalysts or additives, and allow for the generation of a number of important heterocyclic motifs from readily accessible starting materials.
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Keywords
Keywords: Benzofurans; Catalyst loadings; Chemical equations; Chromenes; Co catalysts; High yield; Hydroarylation; Mild reaction; Short reaction time; Starting materials; Terminal alkyne; Synthesis (chemical); Acetylene; alkyne; benzofuran derivative; carbon; chrom
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Source
Journal of Organic Chemistry
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Journal article
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2037-12-31
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