Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation
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Poon, Ivan K. A.
Goodall, Katherine J.
Phipps, Simon
Chow, Jenny D. Y.
Pagler, Eloisa
Andrews, Daniel M.
Conlan, Carly L.
Ryan, Gemma F.
White, Julie A.
Wong, Michael K. L.
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Wiley-VCH Verlag GMBH
Abstract
Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both normal physiological and pathological processes, including
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European Journal of Immunology
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2037-12-31
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