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Glomerular hypertension and hyperfiltration in adrenocorticotrophin-induced hypertension in rats: the role of nitric oxide

Date

Authors

Denton, Kate

Li, Ming

Anderson, Warwick P

Whitworth, Judith

Publisher

Lippincott Williams & Wilkins

Abstract

Objective: To determine the effects on pre- and post-glomerular vascular resistance of adrenocorticotrophin (ACTH)-induced hypertension in rats, before and after blockade of nitric oxide formation. Design: Four groups of Sprague-Dawley rats were studied.

Keywords

Keywords: corticotropin; n(g) nitroarginine; nitric oxide; tetracosactide zinc phosphate; animal experiment; animal model; animal tissue; article; blood pressure monitoring; capillary pressure; controlled study; glomerulus capillary; glomerulus filtration; glomerul Adrenocorticotrophin; Glomerular capillary pressure; Kidney; L-arginine; Nitric oxide synthase inhibition; Post-glomerular resistance; Preglomerular resistance; Renal vascular resistance; Single nephron glomerular filtration rate

URI

http://hdl.handle.net/1885/89205

Collections

ANU Research Publications

Source

Journal of Hypertension

Type

Journal article

DOI

10.1097/00004872-200102000-00021