DDX3X: Taking the stress out on the NLRP3 inflammasome
Date
2019
Authors
Fox, Daniel
Man, Si Ming
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Springer Nature
Abstract
Stress granules and inflammasomes are intracellular complexes that assemble in response to cellular stress signals, enabling cells to persist and perish, respectively. In a recent study published in Nature, Samir et al. identify the helicase DDX3X as a central decision maker in the formation of pro-survival stress granules or pro-death NLRP3 inflammasomes.
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Cell Research
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Journal article
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2037-12-31
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