Impaired pulmonary nitric oxide bioavailability in pulmonary tuberculosis: Association with disease severity and delayed mycobacterial clearance with treatment

Ralph, Anna P; Yeo, Tsin W.; Salome, Cheryl; Waramori, G; Pontororing, Gysje J; Kenangalem, Enny; Sandjaja, .; Tjitra, Emiliana; Lumb, Richard; Maguire, Graeme P.; Price, Ric N; Chatfield, Mark D; Kelly, Paul; Anstey, Nicholas

Impaired pulmonary nitric oxide bioavailability in pulmonary tuberculosis: Association with disease severity and delayed mycobacterial clearance with treatment

Date

2013

Authors

Ralph, Anna P

Yeo, Tsin W.

Salome, Cheryl

Waramori, G

Pontororing, Gysje J

Kenangalem, Enny

Sandjaja, .

Tjitra, Emiliana

Lumb, Richard

Maguire, Graeme P.

Publisher

Elsevier

Abstract

Background. Nitric oxide (NO), a key macrophage antimycobacterial mediator that ameliorates immunopathology, is measurable in exhaled breath in individuals with pulmonary tuberculosis. We investigated relationships between fractional exhale NO (FENO) and