Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation
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Authors
Bornancin, Frederic
Renner, Florian
Touil, Ratiba
Sic, Heiko
Kolb, Yeter
Touil-Allaoui, Ismahane
Rush, James S
Smith, Paul A
Bigaud, Marc
Junker-Walker, Ursula
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American Association of Immunologists
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The paracaspase MALT1 plays an important role in immune receptor-driven signaling pathways leading to NF-κB activation. MALT1 promotes signaling by acting as a scaffold, recruiting downstream signaling proteins, as well as by proteolytic cleavage of mult
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Journal of Immunology
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2037-12-31
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