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Ravenic Acid, a New Tetramic Acid Isolated from a Cultured Microfungus, Penicillium sp.

Date

Authors

Michael, Adam

Grace, Emily

Kotiw, Michael

Barrow, Russell

Publisher

American Chemical Society

Abstract

A new antibiotic polyene tetramic acid, ravenic acid (2), has been isolated from the mycelia of a cultured fungus, Penicillium sp. The structure of ravenic acid was determined by detailed spectroscopic analysis and the major isomer identified as possessing (3Z, 7E, 9E, 11E, 13E) stereochemistry.

Keywords

Keywords: ravenic acid; tetramic acid derivative; unclassified drug; article; carbon nuclear magnetic resonance; drug isolation; drug structure; mycelium; Penicillium; proton nuclear magnetic resonance; spectroscopy; stereochemistry; X ray diffraction; Australia; C

URI

http://hdl.handle.net/1885/92277

Collections

ANU Research Publications

Source

Journal of Natural Products

Type

Journal article

DOI

10.1021/np0200358

Restricted until

2037-12-31

Downloads

File

Description

01_Michael_Ravenic_Acid,_a_New_Tetramic_2002.pdf (47.54 KB)

02_Michael_Ravenic_Acid,_a_New_Tetramic_2002.pdf (53.58 KB)