Asian Schistosomiasis: Current Status and Prospects for Control Leading to Elimination




Gordon, Catherine
Kurscheid, Johanna
Williams, Gail
Clements, Archie
Li, Yuesheng
Zhou, Xiao-Nong
Utzinger, Juerg
McManus, Donald P
Gray, Darren

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MDPI Publishing


Schistosomiasis is an infectious disease caused by helminth parasites of the genus Schistosoma. Worldwide, an estimated 250 million people are infected with these parasites with the majority of cases occurring in sub-Saharan Africa. Within Asia, three species of Schistosoma cause disease. Schistosoma japonicum is the most prevalent, followed by S. mekongi and S. malayensis. All three species are zoonotic, which causes concern for their control, as successful elimination not only requires management of the human definitive host, but also the animal reservoir hosts. With regard to Asian schistosomiasis, most of the published research has focused on S. japonicum with comparatively little attention paid to S. mekongi and even less focus on S. malayensis. In this review, we examine the three Asian schistosomes and their current status in their endemic countries: Cambodia, Lao People’s Democratic Republic, Myanmar, and Thailand (S. mekongi); Malaysia (S. malayensis); and Indonesia, People’s Republic of China, and the Philippines (S. japonicum). Prospects for control that could potentially lead to elimination are highlighted as these can inform researchers and disease control managers in other schistosomiasis-endemic areas, particularly in Africa and the Americas



Asia, control, elimination, epidemiology, Schistosoma japonicum, Schistosoma malayensis, Schistosoma mekongi, schistosomiasis



Tropical Medicine and Infectious Disease


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Open Access

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Creative Commons License (Attribution 4.0 International)



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