Pregnancy and childhood health and developmental outcomes with the use of posthumous human sperm
Date
2015
Authors
Robson, Stephen
Campbell, Simone
McDonald, Janelle
Tremellen, Kelton
Carlin, Emily
Maybury, Genevieve
Journal Title
Journal ISSN
Volume Title
Publisher
British Academy and Oxford University Press
Abstract
Although there is now considerable experience in obtaining sperm from a cadaver, there is little or no published data regarding pregnancy, birth and long-term childhood health and development outcomes when posthumous sperm is used in in vitro fertilisation (IVF). We report the results from treatment of four women undergoing IVF treatment using posthumously acquired human sperm from their deceased partners. In all cases, testicular tissue was obtained in a mortuary setting, and the duration from death to posthumous sperm retrieval ranged from 12 to 48 h. The age of women treated ranged from 31 to 41 years. Fertilization rates ranged from 40 to 100%. Singleton pregnancies were obtained for each of the four women. One pregnancy was complicated by preterm birth at 31 weeks; the other three delivered at term. One baby was growth restricted but morphologically normal; the other children had term birthweights in the normal range. All four children were have shown normal health and developmental outcomes, with the follow-up ranging from 1 to 7 years
Description
Keywords
Citation
Collections
Source
Human Reproduction
Type
Journal article
Book Title
Entity type
Access Statement
License Rights
Restricted until
2037-12-31