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A flow cytometric assay to quantify invasion of red blood cells by rodent Plasmodium parasites in vivo

Lelliott, Patrick M; Lampkin, Shelley; McMorran, Brendan J; Foote, Simon J; Burgio, Gaetan

Description

BACKGROUND Malaria treatments are becoming less effective due to the rapid spread of drug resistant parasites. Increased understanding of the host/parasite interaction is crucial in order to develop treatments that will be less prone to resistance. Parasite invasion of the red blood cell (RBC) is a critical aspect of the parasite life cycle and is, therefore, a promising target for the development of malaria treatments. Assays for analysing parasite invasion in vitro have been developed, but no...[Show more]

CollectionsANU Research Publications
Date published: 2014-03-17
Type: Journal article
URI: http://hdl.handle.net/1885/95525
Source: Malaria Journal
DOI: 10.1186/1475-2875-13-100

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