Skip navigation
Skip navigation

Transcriptome-based exon capture enables highly cost-effective comparative genomic data collection at moderate evolutionary scales

Bi, Ke; Vanderpool, Dan; Singhal, Sonal; Linderoth, Tyler; Moritz, Craig; Good, Jeffrey M.


BACKGROUND To date, exon capture has largely been restricted to species with fully sequenced genomes, which has precluded its application to lineages that lack high quality genomic resources. We developed a novel strategy for designing array-based exon capture in chipmunks (Tamias) based on de novo transcriptome assemblies. We evaluated the performance of our approach across specimens from four chipmunk species. RESULTS We selectively targeted 11,975 exons (~4 Mb) on custom capture arrays, and...[Show more]

CollectionsANU Research Publications
Date published: 2012-08-17
Type: Journal article
Source: BMC Genomics
DOI: 10.1186/1471-2164-13-403


File Description SizeFormat Image
01_Bi_Transcriptome-based_exon_2012.pdfPublished Version1.17 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator