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The Role of P2Y 1 Purinergic Receptors and Cytosolic Ca2 + Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line

Junankar, Pauline; Karjalainen, Ari; Kirk, Kiaran


Exposure of HTC rat hepatoma cells to a 33% decrease in extracellular osmolality caused the cytosolic Ca2+ concentration ([Ca2+]i) to increase transiently by ∼90 nM. This rise in [Ca2+]i was inhibited strongly by apyrase, grade VII (which has a low ATP/

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M204712200


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