A mild, one-pot method for the conversion of carboxylic acids into the corresponding Weinreb amides

Date

2001

Authors

Banwell, Martin
Smith, Jason A

Journal Title

Journal ISSN

Volume Title

Publisher

Marcel Dekker Inc.

Abstract

Reaction of various carboxylic acids with N,O-dimethylhydroxylamine under modified Mukaiyama amide coupling conditions affords the corresponding Weinerb amides in generally high yield.

Description

Keywords

Keywords: amide; antimitotic agent; benzoic acid; carboxylic acid derivative; cinnamic acid; diphenylacetic acid; phenylacetic acid; picoline derivative; pivalic acid; pyrrole derivative; article; chemical reaction; drug synthesis; melting point; methodology; react

Citation

Source

Synthetic Communications

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31