Skip navigation
Skip navigation

Conducting-State Properties of the KcsA Potassium Channel from Molecular and Brownian Dynamics Simulations

Chung, Shin-Ho; Allen, Toby; Kuyucak, Serdar

Description

The mechanisms underlying transport of ions across the potassium channel are examined using electrostatic calculations and three-dimensional Brownian dynamics simulations. We first build open-state configurations of the channel with molecular dynamics simulations, by pulling the transmembrane helices outward until the channel attains the desired interior radius. To gain insights into ion permeation, we construct potential energy profiles experienced by an ion traversing the channel in the...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/92178
Source: Biophysical Journal

Download

File Description SizeFormat Image
01_Chung_Conducting-State_Properties_of_2002.pdf985.36 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator