Synthesis of chiral multidentate tertiary arsines with As4 or As6 donor atoms
Date
2000
Authors
Doyle, Roy
Habermehl, Nicolle
Salem, Geoffrey
Willis, Anthony
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
Reaction of l,l,l-tris(chloromethyl)ethane with ca. three equivalents of sodium or lithium (2-dimethylarsinophenyl)methylarsenide in thf gave several products including the tetra(tertiary arsine) (R*,RAi*)-, (RAs*,SAi*,r*)and (RAs*,5 As*,5*)-l-(chloromethyl)-l,l-bis{[(2- dimethylarsinophenyl)methylarsino]methyl}ethane and the hexa(tertiary arsine) (As*,R As*,ßAs*)-l,l,l-tris{[(2-dimethylarsinophenyl) methylarsino]methyl}ethane. The latter is the first example of a chiral hexa(tertiary arsine). The products from the reaction have been separated by complexation to cobalt(m). The three diastereomers of the tetra(tertiary arsine) each bind to the metal centre in a completely stereoselective manner: the (./?As*As*,r*) and (/?As*,5As*,î*) forms of the ligand each form a single trans dichloro complex and the (AAs*,/?A5*) diastereomer a cis-a complex. The structure of the latter has been confirmed by an X-ray analysis. Three other complexes have also been isolated from this reaction: /ras-dichlorobis[l,2phenylenebis(dimethylarsine)]cobalt(in) chloride, a cis-a complex of the cyclic chiral tetra(tertiary arsine) (A.SAJ./IAR-S.ô.T-pentahydro-ô-f- dimethylarsinophenylJmethylarsinolmethyU-l.ô-trimethylbenzo][ 1,4]diarsacycloheptane and a cobalt(m) complex of the chiral hexa(tertiary arsine). The structures of the latter two complexes have been confirmed by X-ray analyses.
Description
Keywords
Citation
Collections
Source
Dalton Transactions
Type
Journal article