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Skeletal muscle ryanodine receptor channels are activated by the fungal metabolite, gliotoxin

Green, Daniel; Pace, Suzy M; Hurne, Alanna; Waring, Paul; Hart, James; Dulhunty, Angela


Interactions between the reactive disulfide fungal metabolite, gliotoxin (GTX), and rabbit skeletal ryanodine receptor (RyR) calcium release channels have been examined. RyRs in terminal cisternae vesicles formed a covalent complex with 100 μM35S-GTX, wh

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Journal of Membrane Biology
DOI: 10.1007/s002320001070


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