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Channels formed with a mutant prion protein PrP(82-146) homologous to a 7-kDa fragment in diseased brain of GSS patients

Bahadi, Randa; Farrelly, Peter; Kenna, Bronwyn; Kourie, Joseph; Tagliavini, Fabrizio; Forloni, Gianluigi; Salmona, Mario

Description

A major prion protein (PrP) mutant that forms amyloid fibrils in the diseased brain of patients with Gerstmann-Sträussler-Scheinker syndrome (GSS) is a fragment of 7 kDa spanning from residues 81-82 to 144-153 of PrP. Analysis of ionic membrane currents,

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/88488
Source: American Journal of Physiology - Cell Physiology

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