Conversion of (-)-3-Dehydroshikimic Acid into Derivatives of the (+)-Enantiomer
Date
2003
Authors
Banwell, Martin
Edwards, Alison
Essers, Michael
Jolliffe, Katrina
Journal Title
Journal ISSN
Volume Title
Publisher
American Chemical Society
Abstract
(-)-3-DHS (1), a compound available in large quantity through "engineering" of the shikimic acid pathway, has been converted over eight steps into the methyl ester, ent-2, of the (+)-enantiomer. Methyl (+)-shikimate (15) and its C-3 epimer (ent-5) have also been prepared by related means.
Description
Keywords
Keywords: Enantiomers; Chemical reactions; Derivatives; Esters; Organic acids; 3 dehydroshikimic acid; ester derivative; shikimic acid derivative; unclassified drug; article; enantiomer; reaction analysis; stereochemistry; synthesis; Indicators and Reagents; Shikim
Citation
Collections
Source
Journal of Organic Chemistry
Type
Journal article