Synthesis, Electrochemistry, and Bioactivity of the Cyanobacterial Calothrixins and Related Quinones
-
Altmetric Citations
Bernardo, Paul; Chai, Christina; Heath, Graham; Mahon, Peter; Smith, Geoffrey D; Waring, Paul; Wilkes, Bronwyn
Description
The calothrixins are quinone-based natural products isolated from Calothrix cyanobacteria which show potent antiproliferative properties against several cancer cell lines. Preliminary mechanistic studies suggest that the biological mode of action of the calothrixins maybe linked to their ability to undergo redox cycling. In this study we compare the bioactivities of the calothrixins with those of structurally related quinones in order to identify the structural features in the calothrixins...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2004 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/87057 |
Source: | Journal of Medicinal Chemistry |
DOI: | 10.1021/jm049625o |
Download
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator