Comparison of fluorotyrosines and methionine uptake in F98 rat gliomas
-
Altmetric Citations
Langen, Karl-Josef; Jarosch, M; Muhlensiepen, Heinz; Hamacher, Kurt; Broer, Stefan; Jansen, Paul; Zilles, Karl; Coenen, Heinz
Description
The transport mechanisms of O-(2-[18F]fluoroethyl)-L-tyrosine (FET) and 2-[18F]fluoro-L-tyrosine (FTyr) were compared to those of [3H]-Methyl-L-methionine (MET) in F98 rat glioma cells in vitro and by tumor imaging by ex vivo dual tracer autoradiography in F98 rat gliomas. Both, FET and FTyr exhibited similar transport characteristics in F98 glioma cells compared to MET, i.e. mainly a sodium dependent transport similar to system B0,+ and sodium independent transport via system L. Radioactivity...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2003 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/86564 |
Source: | Nuclear Medicine and Biology |
DOI: | 10.1016/S0969-8051(03)00023-4 |
Download
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 23 August 2018/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator