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T Helper-2 Immunity Regulates Bronchial Hyperresponsiveness in Eosinophil-Associated Gastrointestinal Disease in Mice

Forbes, Elizabeth; Prescott, Vanessa; D'Aprile, Angela; Henry, Peter J.; Yang, Ming; Matthaei, Klaus; Rothenberg, Marc E; Foster, Paul S; Hogan, Simon


Background & Aims: Eosinophil-associated gastrointestinal diseases are frequently associated with extraintestinal features, including bronchopulmonary manifestations. The factors predisposing to bronchial hyperresponsiveness in eosinophil-associated gastrointestinal diseases are unknown. To elucidate the mechanistic link between eosinophil-associated gastrointestinal diseases and bronchial hyperresponsiveness, we used murine models of eosinophil-associated gastrointestinal diseases and...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Gastroenterology
DOI: 10.1053/j.gastro.2004.03.057


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