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Location of CNTFR(alpha) on outer segments: Evidence of the site of action of CNTF in rat retina

Valter (Valter-Kocsi), Krisztina; Bisti, Silvia; Stone, Jonathan

Description

Ciliary neurotrophic factor (CNTF) is an important factor in the retina's mechanisms of self-protection. It is generated by retinal glial cells in response to stress, and has a significant protective effect on retinal neurones. In this study we have identified the location of the α component of the CNTF receptor complex (CNTFRα) in rat retina, using immunohistochemistry and high-resolution confocal microscopy. The major location of CNTFRα is on photoreceptor outer segments. More scattered,...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/86176
Source: Brain Research
DOI: 10.1016/S0006-8993(03)03130-5

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