The Mitogen-Induced Increase in T Cell Size Involves PKC and NFAT Activation of Rel/NF-kB-Dependent c-myc Expression
Date
2004
Authors
Grumont, Raelene
Lock, Peter
Shannon, M Frances
Moore, Anna
Gerondakis, Steve
Mollinari, Michael
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Volume Title
Publisher
Cell Press
Abstract
Cell growth during the G1 stage of the cell cycle is partly controlled by inducing c-myc expression, which in B cells is regulated by the NF-κB1 and c-Rel transcription factors. Here, we show that c-myc-dependent growth during T cell activation requires
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Keywords
Keywords: protein kinase C theta; transcription factor Rel; article; cell cycle G1 phase; cell size; gene expression; genetic transcription; nuclear import; oncogene c myc; priority journal; T lymphocyte; T lymphocyte activation; Animals; Cell Size; DNA-Binding Pro
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Source
Immunity
Type
Journal article
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2037-12-31
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