Fat Aussie - A new alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis
Arsov, Todor; Silva, Diego; O'Bryan, Moira K; Sainsbury, Amanda; Lee, Nicola J; Kennedy, Claire L; Manji, Shehnaaz; Nelms, Keats; Liu, Conan; Garcia De Vinuesa, Maria Carola; de Kretser, David M; Goodnow, Christopher; Petrovsky, Nikolai
Mutations in the human ALMS1 gene are responsible for Alström syndrome, a disorder in which key metabolic and endocrinological features include childhood-onset obesity, metabolic syndrome, and diabetes, as well as infertility. ALMS1 localizes to the basa
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