Fat Aussie - A new alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis
Date
2006
Authors
Arsov, Todor
Silva, Diego
O'Bryan, Moira K
Sainsbury, Amanda
Lee, Nicola J
Kennedy, Claire L
Manji, Shehnaaz
Nelms, Keats
Liu, Conan
Garcia De Vinuesa, Maria Carola
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Volume Title
Publisher
Endocrine Society (USA)
Abstract
Mutations in the human ALMS1 gene are responsible for Alström syndrome, a disorder in which key metabolic and endocrinological features include childhood-onset obesity, metabolic syndrome, and diabetes, as well as infertility. ALMS1 localizes to the basa
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Keywords
Keywords: protein fos; ALMS1 gene; Alstrom syndrome; animal cell; animal experiment; animal model; animal tissue; article; audiology; body composition; body weight; cell hyperplasia; cell loss; controlled study; diabetes mellitus; female; fertility; food intake; ge
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Source
Molecular Endocrinology
Type
Journal article
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2037-12-31
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