Aromatic chlorination of ω-phenylalkylamines and ω-phenylalkylamides in carbon tetrachloride and α,α,α-trifluorotoluene

Date

2006

Authors

O'Connell, Jenny
Simpson, Jamie S
Dumanski, Paul
Simpson, Gregory Wayne
Easton, Christopher

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

The aromatic halogenation of simple alkylbenzenes with chlorine proceeds smoothly in acetic acid but is much less efficient in less polar solvents. By contrast chlorination of ω-phenylalkylamines, such as 3-phenylpropylamine, occurs readily in either ace

Description

Keywords

Keywords: Acetic acid; Amines; Carbon inorganic compounds; Organic solvents; Rate constants; Alkylbenzenes; O-chloroimidates; Ortho-chlorinated products; Aromatic compounds; alpha,alpha,alpha trifluorotoluene; alpha,alpha,alpha-trifluorotoluene; amide; carbon tetra

Citation

Source

Organic and Biomolecular Chemistry

Type

Journal article

Book Title

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Restricted until

2037-12-31