Froemke, Robert C.; Letzkus, Johannes; Kampa, Bjoern; Hang, Giao B.; Stuart, Gregory J
While it has been appreciated for decades that synapse location in the dendritic tree has a powerful influence on signal processing in neurons, the role of dendritic synapse location on the induction of long-term synaptic plasticity has only recently been explored. Here, we review recent work revealing how learning rules for spike-timing-dependent plasticity (STDP) in cortical neurons vary with the spatial location of synaptic input. A common principle appears to be that proximal synapses show...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.