Dendritic synapse location and neocortical spike-timing-dependent plasticity
While it has been appreciated for decades that synapse location in the dendritic tree has a powerful influence on signal processing in neurons, the role of dendritic synapse location on the induction of long-term synaptic plasticity has only recently been explored. Here, we review recent work revealing how learning rules for spike-timing-dependent plasticity (STDP) in cortical neurons vary with the spatial location of synaptic input. A common principle appears to be that proximal synapses show...[Show more]
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|Source:||Frontiers in Synaptic Neuroscience|
|01_Froemke_Dendritic_synapse_location_and_2010.pdf||2.06 MB||Adobe PDF||Request a copy|
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