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Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats

Rummery, Nicole; Grayson, Thomas; Hill, Caryl

Description

Objective and design: Remodelling in the media and decreases in connexin (Cx) expression and size of endothelial cells occur in the caudal artery of spontaneously hypertensive rats (SHR). The objective of this study was to determine whether similar changes are found in the aorta and whether effects in both aorta and caudal artery are present in the pre-hypertensive period or can be reversed by antihypertensive treatment. Methods and results: In the aorta of SHR, there was no difference in...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/84322
Source: Journal of Hypertension
DOI: 10.1097/00004872-200502000-00014

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