Heparanase inhibition reduces porteinuria in a model of accelerated anti-glomerular basement membrane antibody disease

Date

2005

Authors

Levidiotis, Vicki
Freeman, Craig
Tikellis, Chris
Cooper, Mark E
Power, David A

Journal Title

Journal ISSN

Volume Title

Publisher

Blackwell Publishing Ltd

Abstract

Background: The β-D-endoglycosidase, heparanase, is emerging as an important contributor to the pathogenesis of proteinuria. The purpose of the present study therefore was to examine the role of heparanase in a model of accelerated anti-glomerular baseme

Description

Keywords

Keywords: glomerulus basement membrane antibody; glycosidase; heparanase; heparanase antibody; messenger RNA; polyclonal antibody; unclassified drug; animal cell; animal experiment; animal model; animal tissue; antibody titer; antiglomerulus basement membrane disea Anti-glomerular basement membrane disease; Heparanase; Proteinuria

Citation

Source

Nephrology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31